Fibrinopeptide B, human TFA

CAS No. ——

Fibrinopeptide B, human TFA ( FPB,human TFA )

Catalog No. M29861 CAS No. ——

FibrinopeptideB,human is a 14-amino acid polypeptide released from the amino terminus of the fibrinogen segment.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Fibrinopeptide B, human TFA
  • Note
    Research use only, not for human use.
  • Brief Description
    FibrinopeptideB,human is a 14-amino acid polypeptide released from the amino terminus of the fibrinogen segment.
  • Description
    FibrinopeptideB,human is a 14-amino acid polypeptide released from the amino terminus of the fibrinogen segment.(In Vitro):Fibrinopeptide B, human is released from the amino-terminus of the B 3-chains of fibrinogen by thrombin. Fibrinopeptide B, human (hFpB, 10 nM) causes directed cell migration of neutrophils (PMN), and fibroblasts. Fibrinopeptide B, human also possesses potent chemotactic activity relative to human complement (C5a), leukotriene B4 (LTB4), and formyl-methionylleucyl-phenylalanine (fMLP), and for fibroblasts its chemotactic activity is comparable to that of platelet-derived growth factor. However, Fibrinopeptide B, human is not chemotactic for monocytes, and shows no interaction with PMN receptor for C5a, LTB4, or fMLP.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    FPB,human TFA
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    1666.58
  • Molecular Formula
    C68H94F3N19O27
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    Sequence:{Glp}-Gly-Val-Asn-Asp-Asn-Glu-Glu-Gly-Phe-Phe-Ser-Ala-Arg

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

Senior RM, et al. Effects of fibrinogen derivatives upon the inflammatory response. Studies with human fibrinopeptide B. J Clin Invest. 1986 Mar;77(3):1014-9.
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